Rosetta Commons

The first close to atomic-level resolution, blind ab initio structure predictionCASP6 T281, Image: Dr. Phil Bradley

Members

University of Washington

University of North Carolina at Chapel Hill

Johns Hopkins University

University of California Santa Cruz

University of California San Francisco

New York Universiy

Los Alamos National Lab

Rosetta Design Group

Associates

Objexx Engineering

Rosetta Commons

Rosetta Commons aims to develop high resolution protein prediction and design software and make this software broadly available to the scientific community without reach-through or other restrictive terms. The Rosetta Commons provides for an environment of continuous sharing and collaborative development in the context of the Rosetta platform.

The Rosetta++ software focuses on the prediction and design of protein structures, protein folding mechanisms, and protein-protein interactions. The Rosetta codes have been repeatedly successful in the Critical Assessment of Techniques for Protein Structure Prediction (CASP) competition as well as the CAPRI competition and have been modified to address additional aspects of protein design, docking and structure.

This software is currently licensed for free to hundreds of academic labs in 32 countries, as well as on a fee-basis to drug discovery companies. The code is also the foundation for the Human Proteome Folding Project on the World Community Grid. Revenue generated to date has been utilized for continued software development.