Rosetta Documentations

Rosetta Software documentations are available at the RosettaCommon's internal tikiwiki. There is a Quick Start to warm you up with the Rosetta Software Suit. The User Guide also has detailed documents for each mode in the Software Suite.

Index of Major Contents

File Introduction

Commons and Options

Functionality -- Ab Initio Structure Prediction

Functionality -- Sequence Design

Functionality -- Protein-protein Docking

Functionality -- Fragment Library

Source Codes Overview

Rosetta Scripts

Rosetta Database

New features of the current release

One of the Ran's binding partners 1A2K.pdb which was predicted by the design simulations. (Humphris EL, Kortemme T., PLoS Comput Biol. 2007 Aug;3(8):e164. Epub 2007 Jul 5.Click here to read.)

Antibody modeling: Predicts antibody structures using knowledge-based techniques, de novo loop modeling, and docking.

Ensemble docking: This ensemble docking method is compatible with all other major methods and protocols in protein-protein docking in RosettaDock except standard prepacking and symmetry docking.

Domain insertion: The domain insertion mode of Rosetta++ models domain insertion proteins, where in the protein is made up of two domains, and the second domain is inserted into the sequence of the first domain.

FunHunt Scripts: FunHunt is an SVM based classifier for the discrimination of the near native orientation of a protein complex from spurious low energy orientations. The classification is based on the local energy funnel characteristics.

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