Rosetta Commons drives innovation in biomolecular modeling and design through cutting-edge computational methods and shared software. Our global community of scientists collaborates to advance open, reproducible science and accelerate discovery.
Latest News
REU Trainees’ Research Projects Highlight Exciting First Steps in Biomolecular Research
REU trainee Tony Peonio presenting his lightning talk at Summer RosettaCon 2026. This is part…
A Summer of Science: REU Trainees Conduct Research at Host Labs, Present at Summer RosettaCon 2026
Featured image is the 2026 REU cohort with Program Manager Camille Mathis and PI Jeffrey…
Coding, Collaboration, and Camaraderie: REU Trainees’ Introductory Bootcamp 2026
Featured image is of Code School 2026 attendees, including REU trainees, instructors Nate Felbinger and…
Two-phase computational pipeline yields high-affinity de novo BMP-2 binders for bone regeneration
Key Takeaways By combining Rosetta-based motif grafting with deep-learning tools like RFdiffusion, ProteinMPNN, and AlphaFold2,…
De Novo Protein Design Overcomes Gene Editing Limits to Sustain CAR-T and TCR-T Cell Function
Key Takeaways De novo designed proteins bind and modulate entire target families simultaneously, bypassing the…
New OpenBind-0 model and dataset benchmark co-folding tools in drug discovery
Key Takeaways OpenBind-0 (OB0) is a fully open-source co-folding model built on OpenFold3, trained on…
Integrating Mass Spectrometry Restraints into Rosetta and AlphaFold Modeling Pipelines
Key Takeaways Integrating mass spectrometry data with computational modeling platforms like Rosetta and AlphaFold2 improves…
Brazil’s Largest Open Science Event Introduces Thousands to Protein Design with Foldit
For the second year in a row, Brazil’s largest open science event introduced thousands of…
Motivated Trainees and Tutors Shine at FEBS Advanced Practical Course
On April 19-24, 2026, 36 international participants gathered in Blankenberge, Belgium, for the FEBS Advanced…
Upcoming Events
Summer RosettaCon 2026 is on August 3 - 7, 2026, at the University of Washington in Seattle, WA.
European RosettaCon is October 28 - 30, 2026, at NOVA University Lisbon in Portugal.