So, I have a pdb complex of a virus and antibody and I wanted to compute the binding energy of the given complex. I know that I need to use InterfaceAnalyzer for this task, but the problem is that the input of the InterfaceAnalyzer application is a resfile. So, how am I supposed to connect these two, the resfile and the pdb file ?
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You don't need a resfile to run InterfaceAnalyzer. It's optional. If you want to give the code instructions about how it repacks the unbound structures, the resfile lets you do that.
As for "how to write a resfile" - have you seen the resfile documentation page? I can answer further if it confused you. https://www.rosettacommons.org/docs/latest/resfiles.html