Application created by Dr. Jared Adolf-Bryfogle ( and Dr. Jason Labonte (, in collaboration with Dr. Sebastian Rämisch (

PIs: Dr. William Schief ( and Dr. Jeffrey Gray (


App: glycan_relax

Glycan Relax aims to sample potential conformational states of carbohydrates, either attached to a protein or free. It is extremely fast. Currently, it uses a few strategies to do so, using statistics from various papers, the CHI (CarboHydrate Intrinsic) energy term, and a new framework for backbone dihedral sampling. Conformer statistics adapted from Schief lab Glycan Relax app, originally used/written by Yih-En Andrew Ban.

It can model glycans from ideal geometry, or refine already-modeling glycans.

See Working With Glycans for more.

See Also