BestHotspotCst

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BestHotspotCst

Removes Hotspot BackboneStub constraints from all but the best_n residues, then reapplies constraints to only those best_n residues with the given cb_force constant. Useful to prune down a hotspot-derived constraint set to avoid getting multiple residues getting frustrated during minimization.

<BestHotspotCst name="(&string)" chain_to_design="(2 &integer)" best_n="(3 &integer)" cb_force="(1.0 &Real)"/>

best_n: how many residues to cherry-pick. If there are fewer than best_n residues with constraints, only those few residues will be chosen.
chain_to_design: which chain to reapply constraints
cb_force: Cbeta force to use when reapplying constraints

BestHotspotCst

BestHotspotCst

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