class definition for a profile-profile scoring scheme for comparing two sequence profiles using the L1 city-block distance.
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class definition for a profile-profile scoring scheme for comparing two sequence profiles using the L1 city-block distance.
- Detailed: Simply based on comparing single profiles from two protein
- sequences by computing the sum of P(A) - P(B) for all matching probabilities in the profiles A and B. Also includes with affine gap penalties of the form penalty = A + Bk, where A represents the penalty for starting a gap, and B represents the penalty for extending a previously opened gap by k characters.
- Author
- James Thompson