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Problem with the top 25 fragments used in the library of 200 nine-residue fragments in AbinitioRelax

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Problem with the top 25 fragments used in the library of 200 nine-residue fragments in AbinitioRelax
#1

Hi,all.

I'm confused about the reason for using the top  25 fragments in the library of 200 nine-residue fragments in AbinitioRelax.Instead,for the library of 200 three-residue fragments,all fragments are applied in the process of fragment assembly.

Post Situation: 
Wed, 2017-07-26 01:12
MA

Talking with someone familiar with the protocol, the limitation is because the fragment quality gets worse for the later fragments, and it's been found heuristically that  using fragments beyond the top 25 gives worse results with a reasonable amount of sampling. 

Mon, 2017-08-21 09:55
rmoretti