I wanted to pick your brains. I am using KIC with fragments to modell a loop. I am under the impression that this protocol outperfromrs the next generation KIC. Could you confirm this for me and perhap refer me to the relevant paper? Is the KIC with fragment protocol better?
Alternatively, can I use the KIC with fragments protocol with the flags from next generation KIC?
Lastly, I wanted to ask whether the KIC with fragments and Floopy Tail protocols take into the account the waters. Are these run in the explicit solvent?
Thank you very much for your help!