I was wondering whether Remodel is currently compatible with the RosettaMP framework? I have a designed membrane protein and I'm trying to alter the sequence of water-exposed loops, which involves a few insertions. I'm using Remodel to do this but haven't been able to run it using the franklin2019 scorefunction.
Here are the flags that I'm using:
-s protein.pdb \
-remodel:blueprint protein_new_loops.bp \
-score:weights franklin2019 \
-ex1 -ex2 \
-mp:setup:spanfiles protein.span \
-database /mnt/storage/software/apps/Rosetta-3.12/rosetta_bin_linux_2020.08.61146_bundle/main/database \
-remodel:num_trajectory 1000 -remodel:save_top 10 \
-out:path:all output -out:suffix $SLURM_JOBID \
When trying to run using these flags, I get the following error:
[ ERROR ] UtilityExitException
ERROR: Incomplete Conformation: Trying to access membrane framework data without initializing with AddMembraneMover. Exiting!
Any help would be greatly appreciated