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Piecing together multiple domains

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Piecing together multiple domains

If I have the separate domains of a protein, determined by rosetta, can I connect them in a simulation, keeping the pre-determined domains rigid and only allowing flexibility at the new connections?

Mon, 2009-06-22 14:24

you can try using domain insertion mode of rosetta. Have you read the documentation on that? It may suit your purpose.

Tue, 2009-07-14 13:58