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contents of span file

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contents of span file
#1

Hello,

Should the spanfile supplied to -in:file:spanfile option contain only the transmbrane helices or the trasnmembrane loops and sheets too?

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Mon, 2013-04-15 05:01
tevang

The code that reads the spanfile (rosetta_source/src/core/scoring/MembraneTopology.cc:initialize) is chock-full of the construction "tmhelix" and similar - in other words, I think it is only looking for transmembrane helices. I'm not even sure that this code allows things other than helix (the papers I've seen don't suggest that it does, nor does the documentation).

Mon, 2013-04-15 08:16
smlewis