I'm a postgraduate student, interested in protein structure prediction.
I noticed that the document said:
- Abinitio: max 150 amino acids are cosidered possible
So, I want to know, how to use rosetta to predict number of protein of amino acids more than 150 (e.g. 500)?
- Is it a good idea to divide it into several domain segmentations, and predict them along?
- If we do as above, how to determine domain regions, and how to assemble them to a full-length structural model?
Any help would be appreciated.